Data Material
ALK Medical Affairs Canada provides the resources found on this website for Canadian healthcare professionals only.
Prevalence of Eosinophilic Esophagitis in Sublingual Immunotherapy Tablet Clinical Trials is Similar to the Background Prevalence in an Atopic Population
Congress Material• Eosinophilic esophagitis (EoE) is an allergen-mediated inflammatory condition of the esophagus
• The prevalence of EoE in the general population is approximately 0.1% and is observed to be
higher in adults than children
• Patients with EoE often have comorbid allergic disease (i.e., allergic rhinitis, asthma, eczema,
food allergy), known as atopy
• The presence of atopic disease is known to increase the risk of developing EoE
• There is currently limited prevalence data for EoE in atopic populations, although recent studies
have estimated the prevalence of EoE in atopic populations as 8.0-16.5% in adults and 0.2% to
5% in children
• Sublingual immunotherapy (SLIT)-tablets are an effective treatment for allergic rhinitis with or
without conjunctivitis (AR/C)
• Reports of EoE associated with SLIT-tablets are rare